Powder: -20°C for 3 years | In solvent: -80°C for 1 year
L-2-Hydroxyglutaric acid, an epigenetic modifier and potential oncometabolite in renal cancer, impedes mitochondrial creatine kinase (Mi-CK) activity, exhibiting Km and Ki values of 2.52 mM and 11.13 mM, respectively. Additionally, it obstructs histone demethylases, thereby encouraging histone methylation.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 約 35 days | ¥ 18,000 |
5 mg | 約 35 days | ¥ 57,500 |
10 mg | 約 35 days | ¥ 80,000 |
25 mg | 約 35 days | ¥ 136,500 |
説明 | L-2-Hydroxyglutaric acid, an epigenetic modifier and potential oncometabolite in renal cancer, impedes mitochondrial creatine kinase (Mi-CK) activity, exhibiting Km and Ki values of 2.52 mM and 11.13 mM, respectively. Additionally, it obstructs histone demethylases, thereby encouraging histone methylation. |
In vitro | L-2-Hydroxyglutaric acid effectively inhibits 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs), such as the Ten Eleven Translocation (TET) enzymes. |
別名 | (S)-2-Hydroxyglutaric acid |
分子量 | 148.11 |
分子式 | C5H8O5 |
CAS No. | 13095-48-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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L-2-Hydroxyglutaric acid 13095-48-2 Others (S)-2-Hydroxyglutaric acid L2Hydroxyglutaric acid 2-Hydroxyglutaric acid L 2 Hydroxyglutaric acid Inhibitor inhibitor inhibit