store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
L-NIL is a potent and selective inhibitor of inducible NO synthase with IC50s of 92 and 3.3 μM for rat brain constitutive NO synthase and mouse inducible NO synthase, respectively.
ターゲット&IC50 | iNOS (mouse):3.3 μM , cNOS (rat brain):92 μM |
In vitro | L-NIL exhibits 28-fold higher selectivity for mouse inducible NOS (miNOS) over rat brain constitutive NOS (rcNOS), with IC50 values of 3.3 pM and 92 pM, respectively. Furthermore, it demonstrates roughly 6 times more potency towards miNOS compared to both L-NMA and L-NNA. The compound effectively inhibits miNOS and rcNOS in a concentration-dependent manner, showcasing significant potency for miNOS. |
分子量 | 187.24 |
分子式 | C8H17N3O2 |
CAS No. | 53774-63-3 |
store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
L-NIL 53774-63-3 Others L NIL LNIL Inhibitor inhibitor inhibit