Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 176,000 |
50 mg | 約6-8 週間 | ¥ 228,500 |
100 mg | 約6-8 週間 | ¥ 346,500 |
説明 | LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively. |
ターゲット&IC50 | DYRK2:48 nM , Haspin:10 nM |
In vitro | LDN-192960 hydrochloride (10 μM) is inhibits ten of the other kinases by ≥90%, with only five being potently inhibited (IC50<1 μM), including CLK1 (IC50=0.21 μM), DYRK1A (IC50= 0.10 μM), DYRK2 (IC50=2 nM), DYRK3 (IC50=19 nM) and PIM1 (IC50=0.72 μM)[1]. |
分子量 | 401.35 |
分子式 | C18H22Cl2N2O2S |
CAS No. | 2309172-48-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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LDN-192960 hydrochloride 2309172-48-1 Others LDN192960 hydrochloride LDN192960 Hydrochloride LDN 192960 Hydrochloride LDN-192960 Hydrochloride LDN 192960 hydrochloride Inhibitor inhibitor inhibit