Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LY2955303 is an effective and selective retinoic acid receptor gamma (RARγ) antagonist (Ki: 1.09 nM).
説明 | LY2955303 is an effective and selective retinoic acid receptor gamma (RARγ) antagonist (Ki: 1.09 nM). |
ターゲット&IC50 | RARγ:1.09 nM(ki) |
In vitro | The functional Ki for RARγ is 7.1±4.9 nM. LY2955303 is tested and observed that the binding Kis for RARα, RARβ, and RARγ are >1700, >2980, and 1.09 nM, respectively . |
In vivo | LY2955303(p.o.) shows a dose-responsive effect whereby the rat decreases differential weight-bearing (ED50=0.72 mg/kg). |
分子量 | 578.74 |
分子式 | C36H42N4O3 |
CAS No. | 1433497-19-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (43.20 mM), Sonication and heating are recommended.
You can also refer to dose conversion for different animals. 詳細
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LY2955303 1433497-19-8 Metabolism Others Retinoid Receptor inhibit Autophagy Retinoic acid receptors RAR/RXR Inhibitor LY 2955303 Retinoid X receptors LY-2955303 inhibitor