Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa cells through the induction of apoptosis. This process is mediated by caspase-3 activation. In refractory prostate cancer cells, Lycopodine triggers apoptosis by modulating 5-lipoxygenase and depolarizing the mitochondrial membrane potential, without altering p53 activity.
説明 | Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa cells through the induction of apoptosis. This process is mediated by caspase-3 activation. In refractory prostate cancer cells, Lycopodine triggers apoptosis by modulating 5-lipoxygenase and depolarizing the mitochondrial membrane potential, without altering p53 activity. |
分子量 | 247.38 |
分子式 | C16H25NO |
CAS No. | 466-61-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Lycopodine 466-61-5 Apoptosis Metabolism Proteases/Proteasome Caspase Lipoxygenase Inhibitor inhibitor inhibit