Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MGAT2-IN-1 is an orally active monoacylglycerol acyltransferase (MGAT2)inhibitor (human and mouse MGAT2 with IC50 of 7.8 and 2.4 nM , respectively).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
5 mg | 約10-14 週間 | ¥ 108,000 |
25 mg | 約10-14 週間 | ¥ 383,500 |
50 mg | 約10-14 週間 | ¥ 500,500 |
100 mg | 約10-14 週間 | ¥ 799,000 |
1 mL * 10 mM (in DMSO) | 約10-14 週間 | ¥ 170,000 |
説明 | MGAT2-IN-1 is an orally active monoacylglycerol acyltransferase (MGAT2)inhibitor (human and mouse MGAT2 with IC50 of 7.8 and 2.4 nM , respectively). |
ターゲット&IC50 | MGAT2 (mouse):2.4 nM , MGAT2 (human):7.8 nM |
In vivo | In the lipid utilization analysis, MGAT2-IN-1 significantly increases free fatty acid (FFA) and acylcarnitine levels. MGAT2-IN-1 (30 mg/kg) also significantly reduces food intake dose dependently, suppresses BW gains. MGAT2-IN-1 shows anti-diabetic effects in mice[1]. |
分子量 | 654.01 |
分子式 | C27H21ClF5N7O3S |
CAS No. | 1800025-30-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (191.13 mM)
You can also refer to dose conversion for different animals. 詳細
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MGAT2-IN-1 1800025-30-2 Others MGAT2 IN 1 MGAT-2-IN-1 MGAT2IN1 Inhibitor inhibitor inhibit