Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MK 0893 is a potent, selective antagonist of glucagon receptor.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
5 mg | 約8-10 週間 | ¥ 82,500 |
25 mg | 約8-10 週間 | ¥ 429,500 |
50 mg | 約8-10 週間 | ¥ 635,500 |
100 mg | 約8-10 週間 | ¥ 1,136,000 |
説明 | MK 0893 is a potent, selective antagonist of glucagon receptor. |
ターゲット&IC50 | Glucagon receptor:6.6 nM |
In vitro | MK 0893 is active against the rhesus monkey GCGR(IC50 of 56 nM in a cAMP assay with CHO cells expressing the rhesus GCGR)[1]. |
In vivo | In hGCGR mice on a high fat diet, MK 0893 at 3, and 10 mpk po in feed lowers blood glucose levels by 89% and 94% at day 10, respectively, relative to the difference between the vehicle control and lean hGCGR mice[1]. |
分子量 | 588.48 |
分子式 | C32H27Cl2N3O4 |
CAS No. | 870823-12-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 33.33 mg/mL (56.64 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MK 0893 870823-12-4 Others MK-0893 MK0893 Inhibitor inhibitor inhibit