Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 7,500 | |||
5 mg | 在庫あり | ¥ 16,000 | |||
10 mg | 在庫あり | ¥ 22,500 | |||
25 mg | 在庫あり | ¥ 36,500 | |||
50 mg | 在庫あり | ¥ 55,000 | |||
100 mg | 在庫あり | ¥ 73,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 18,000 |
説明 | Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA. |
In vitro | Immunocytochemical methods were used to measure the accumulation of phosphorylated H2AX (γH2AX) foci following ionizing radiation (IR) in patient-derived lymphoblastoid cells exposed to methylproamine. Pulsed field gel electrophoresis DNA damage and repair assays were performed to directly interrogate the action of methylproamine on DNA in irradiated cells.Methylproamine-treated cells had fewer γH2AX foci after IR compared to untreated cells. Also, the presence of methylproamine decreased the amount of lower molecular weight DNA entering the gel[2]. |
分子量 | 465.59 |
分子式 | C28H31N7 |
CAS No. | 188247-01-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (118.13 mM)
You can also refer to dose conversion for different animals. 詳細
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Methylproamine 188247-01-0 Others Inhibitor Radioprotector DNA/RNA Synthesis inhibit DNA double-strand inhibitor