Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A) (IC50s: 0.86 and 1.3 μM, respectively). Opiranserin displays antagonistic activity on rP2X3 (IC50=0.87 μM).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A) (IC50s: 0.86 and 1.3 μM, respectively). Opiranserin displays antagonistic activity on rP2X3 (IC50=0.87 μM). |
ターゲット&IC50 | GlyT2:0.86 μM, 5-HT2A receptor:1.3 μM, P2X3 (rat):0.87 μM |
分子量 | 394.51 |
分子式 | C21H34N2O5 |
CAS No. | 1441000-45-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Opiranserin 1441000-45-8 GPCR/G Protein Membrane transporter/Ion channel Neuroscience 5-HT Receptor P2X Receptor GlyT Glycine transporters postoperative VVZ-149 Serotonin Receptor 5-hydroxytryptamine Receptor VVZ 149 pain Inhibitor non-opioid P2XRs anti-inflammatory VVZ149 analgesic inhibit inhibitor