keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PACAP (1-27), human, ovine, rat acetate (PACAP 1-27 acetate) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 35,500 | |||
5 mg | 在庫あり | ¥ 103,500 | |||
10 mg | 在庫あり | ¥ 152,500 | |||
25 mg | 在庫あり | ¥ 226,500 | |||
50 mg | 在庫あり | ¥ 319,000 | |||
100 mg | 在庫あり | ¥ 431,500 |
説明 | PACAP (1-27), human, ovine, rat acetate (PACAP 1-27 acetate) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats. |
In vitro | Radioligand receptor binding assays with I-monoiodinated PACAP (1-27), human, ovine, rat confirms the presence of PAC -receptors on AR4-2J cells, since PACAP (1-27), human, ovine, rat and PACAP(1–38) equipotently displaces radioligand binding with a Kd of 1-2 nM, whereas vasoactive intestinal peptide (VIP) is 1000-fold less potent. PACAP (1-27), human, ovine, rat exhibits a distinct and much higher susceptibility to VIP-amino acid substitutions. PACAP (1-27), human, ovine, rat has potency and binding affinity to stimulate IP3 and cAMP formation in AR4-2J cells[2]. |
In vivo | The inhibitory effect of pituitary adenylate cyclase activating polypeptide (PACAP (1-27), human, ovine, rat) on the increase in total pulmonary resistance (RL) causes either by allergen or histamine in anaesthetized, ventilated guinea-pigs is studied. PACAP (1-27), human, ovine, rat given via i.v. infusion (0.045-4.5 nmol/kg/min) dose-dependently reduces the increase in RL caused by inhaled ovalbumin and histamine. At the highest dose, PACAP (1-27), human, ovine, rat prevented the increase in RL caused by ovalbumin and histamine completely. Infusion of PACAP (1-27), human, ovine, rat and the β2-adrenoceptor agonist, salbutamol (0.045-4.5 nmol/kg/min) inhibit the increase in RL similarly, but salbutamol increases the heart rate more than PACAP (1-27), human, ovine, rat[3]. |
別名 | PACAP 1-27 acetate, PACAP (1-27), human, ovine, rat acetate(127317-03-7 free base) |
分子量 | 3207.71 |
分子式 | C144H228N40O41S |
CAS No. | TP1070L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mM
You can also refer to dose conversion for different animals. 詳細
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PACAP (1-27), human, ovine, rat acetate TP1070L GPCR/G Protein PACAP PACAP (127), human, ovine, rat acetate PACAP 1-27 Acetate PACAP (1 27), human, ovine, rat acetate PACAP 1-27 acetate PACAP , human, ovine, rat Acetate PACAP (1-27), human, ovine, rat acetate(127317-03-7 free base) Inhibitor inhibitor inhibit