Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PIM447 is a potent, orally available, and selective inhibitor of pan-PIM kinase(PIM1, PIM2, and PIM3 with Ki values of 6, 18, and 9 pM , respectively).
説明 | PIM447 is a potent, orally available, and selective inhibitor of pan-PIM kinase(PIM1, PIM2, and PIM3 with Ki values of 6, 18, and 9 pM , respectively). |
In vitro | PIM447 shows antiproliferative effect on the multiple myeloma (MM) cells,and induces apoptosis[2]. |
In vivo | PIM447 reduces tumor burden[2]. |
別名 | LGH447 |
分子量 | 440.46 |
分子式 | C24H23F3N4O |
CAS No. | 1210608-43-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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PIM447 1210608-43-7 Others LGH 447 PIM 447 LGH447 PIM-447 LGH-447 Inhibitor inhibitor inhibit