Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Propargyl-PEG5-amine is a non-cleavable linker compound, employed in the synthesis of antibody-drug conjugates (ADCs) and PROTACs. It is PEG-based and serves as a connector in the formation of ADCs and PROTACs[1].
説明 | Propargyl-PEG5-amine is a non-cleavable linker compound, employed in the synthesis of antibody-drug conjugates (ADCs) and PROTACs. It is PEG-based and serves as a connector in the formation of ADCs and PROTACs[1]. |
In vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
分子量 | 275.34 |
分子式 | C13H25NO5 |
CAS No. | 1589522-46-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Propargyl-PEG5-amine 1589522-46-2 Others Propargyl-PEG-5-amine Propargyl PEG5 amine PropargylPEG5amine Inhibitor inhibitor inhibit