Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RIP1 kinase inhibitor 1 is an orally available and brain-penetrating inhibitor of RIP1 kinase with pKi of 9.04.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 275,500 |
50 mg | 約10-14 週間 | ¥ 360,500 |
100 mg | 約10-14 週間 | ¥ 548,500 |
説明 | RIP1 kinase inhibitor 1 is an orally available and brain-penetrating inhibitor of RIP1 kinase with pKi of 9.04. |
ターゲット&IC50 | RIP1 kinase:pki:9.04 |
In vitro | RIP1 kinase inhibitor 1 strongly suppresses necroptotic cell death and phosphorylation of MLKL(pMLKL) in human colorectal adenocarcinoma HT-29 cells with IC50 of 2 nM and 1.3 nM for nectoptosis and pMLKL) as well as mouse L-cells NCTC 929 (nectoptosis, IC50=15 nM; pMLKL, IC50=2.7 nM). |
分子量 | 461.9 |
分子式 | C24H20ClN5O3 |
CAS No. | 2095515-38-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
RIP1 kinase inhibitor 1 2095515-38-9 Others RIP-1 kinase inhibitor 1 Inhibitor inhibitor inhibit