Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 555,500 |
50 mg | 約10-14 週間 | ¥ 730,000 |
100 mg | 約10-14 週間 | ¥ 987,000 |
説明 | Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively). |
ターゲット&IC50 | TPH1:33 nM, TPH2:7 nM, 5-HT: |
In vivo | Rodatristat (10-50 mg/kg; p.o.; mice) treatment reduces intestinal 5-HT concentrations at 50 mg/kg. Their efficacy drops off significantly at the lower 10 mg/kg dose [1]. |
別名 | KAR5417 |
分子量 | 561.98 |
分子式 | C27H27ClF3N5O3 |
CAS No. | 1673568-73-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Rodatristat 1673568-73-4 Others KAR5417 KAR-5417 KAR 5417 Inhibitor inhibitor inhibit