Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rp-cAMPS triethylammonium salt is an analog of cAMP.It acts as a potent, competitive and cell-permeable antagonist of cAMP-induced activation of cAMP-dependent PKA I and II with Kis of 6.05 µM and 9.75 µM, respectively.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
500 μg | 約 35 days | ¥ 45,000 |
1 mg | 約 35 days | ¥ 68,500 |
5 mg | 約 35 days | ¥ 266,500 |
ターゲット&IC50 | PKA II:9.75 µM (ki), PKA I:ki: 6.05 µM |
In vivo | The monosynaptic excitatory postsynaptic currents (EPSCs) induced at the PB-CeLC and BLA-CeLC synapses in tissue slices from arthritic rats were significantly reduced following treatment with Rp-cAMPS (10 μM, 15 min), whereas no reduction was observed in control neurons from healthy animals. This decline in EPSCs due to Rp-cAMPS is notably substantial when compared to the predrug artificial cerebrospinal fluid (ACSF) baseline levels measured in the identical neurons[1]. |
分子量 | 446.46 |
分子式 | C16H27N6O5PS |
CAS No. | 151837-09-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Rp-cAMPS triethylammonium salt 151837-09-1 Others Rp cAMPS triethylammonium salt Rp-cAMPS triethylammonium RpcAMPS triethylammonium salt Inhibitor inhibitor inhibit