Powder: -20°C for 3 years | In solvent: -80°C for 1 year
S-8510 is a GABA-A receptor inverse agonist. S-8510 selectively potentiated pentylenetetrazol-induced convulsion without affecting minimal electroconvulsive shock- or strychnine-induced convulsion in ddY mice. S-8510 ameliorated memory impairment induced by cholinergic deficit in the water maze paradigm of Wistar rats. S-8510 augmented LTP of the Schaffer collateral/commissural fiber-CA1 synapses in the hippocampal slice preparations of SD rat. S-8510 increased the extracellular levels of acetylcholine and noradrenaline in the hippocampus of Wistar rat.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 521,000 |
50 mg | 約10-14 週間 | ¥ 684,000 |
100 mg | 約10-14 週間 | ¥ 918,000 |
説明 | S-8510 is a GABA-A receptor inverse agonist. S-8510 selectively potentiated pentylenetetrazol-induced convulsion without affecting minimal electroconvulsive shock- or strychnine-induced convulsion in ddY mice. S-8510 ameliorated memory impairment induced by cholinergic deficit in the water maze paradigm of Wistar rats. S-8510 augmented LTP of the Schaffer collateral/commissural fiber-CA1 synapses in the hippocampal slice preparations of SD rat. S-8510 increased the extracellular levels of acetylcholine and noradrenaline in the hippocampus of Wistar rat. |
別名 | SB 737552, SB-737552, S8510, SB737552, S-8510, S 8510 |
分子量 | 242.23 |
分子式 | C12H10N4O2 |
CAS No. | 151224-83-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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S-8510 free base 151224-83-8 SB 737552 S 8510 free base SB-737552 S8510 SB737552 S-8510 S 8510 S8510 free base Inhibitor inhibitor inhibit