Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sterculic acid, a stearoyl-CoA desaturase-1 (SCD1) inhibitor, effectively suppresses delta-9 desaturase (Δ9D) activity in a dose-dependent manner, exhibiting an inhibition concentration (IC50) value of 0.9 μM [1].
説明 | Sterculic acid, a stearoyl-CoA desaturase-1 (SCD1) inhibitor, effectively suppresses delta-9 desaturase (Δ9D) activity in a dose-dependent manner, exhibiting an inhibition concentration (IC50) value of 0.9 μM [1]. |
In vitro | Sterculic acid (SA), a cyclopropene fatty acid derived from Sterculia foetida seeds, exhibits diverse biological activities, including the reduction of adrenomedullin expression (AP, RP, APS, IML, in preparation) and mediating anti-inflammatory and protective effects. It also demonstrates a potent luteolytic effect in ovines by inhibiting progesterone synthesis, leading to luteal regression [2]. |
In vivo | Sterculic acid is suggested as a promising intervention for metabolic syndrome (MS), as it effectively inhibits the function of stearoyl-CoA desaturase-1 (SCD1) in vivo [3]. |
分子量 | 294.47 |
分子式 | C19H34O2 |
CAS No. | 738-87-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Sterculic acid 738-87-4 Inhibitor inhibitor inhibit