Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sulfo-ara-F-NMN is an analogue of nicotinamide mononucleotide (NMN) with cellular permeability. Sulfo-ara-F-NMN was selective to activate SARM1 and inhibited CD38 with an IC50 of about 10 μM. Activation by Sulfo-ara-F-NMN to Z-48 or NMN, which has a higher cyclase activity, causes conformational changes in SARM1, resulting in cADPR production, NAD depletion, and non-apoptotic cell death.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 569,500 |
50 mg | 約6-8 週間 | ¥ 916,000 |
100 mg | 約6-8 週間 | ¥ 1,443,500 |
説明 | Sulfo-ara-F-NMN is an analogue of nicotinamide mononucleotide (NMN) with cellular permeability. Sulfo-ara-F-NMN was selective to activate SARM1 and inhibited CD38 with an IC50 of about 10 μM. Activation by Sulfo-ara-F-NMN to Z-48 or NMN, which has a higher cyclase activity, causes conformational changes in SARM1, resulting in cADPR production, NAD depletion, and non-apoptotic cell death. |
別名 | CZ-48 |
分子量 | 352.28 |
分子式 | C11H14FN2O6PS |
CAS No. | 1374663-29-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Sulfo-ara-F-NMN 1374663-29-2 Others SulfoaraFNMN Sulfo ara F NMN CZ 48 CZ-48 CZ48 Inhibitor inhibitor inhibit