keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TRα and TRβ, respectively) that can be used to study diseases caused by endocrine abnormalities.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
5 mg | 在庫あり | ¥ 120,000 |
25 mg | 約8-10 週間 | ¥ 372,000 |
50 mg | 約8-10 週間 | ¥ 484,500 |
100 mg | 約8-10 週間 | ¥ 750,500 |
説明 | TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TRα and TRβ, respectively) that can be used to study diseases caused by endocrine abnormalities. |
ターゲット&IC50 | Thyroid hormone β:22 nM, THRα:36 nM |
In vitro | TR antagonist 1 is a high-affinity thyroid hormone receptor (TR) antagonist with IC50 s of 36 and 22 nM for TRα and TRβ, respectively[1]. |
In vivo | In the cholesterol-fed rat model, treatment with TR antagonist 1 reduces heart rate and shows a tendency to increase the proportion of low-density lipoprotein cholesterol (LDL-C) to a certain extent [1]. |
分子量 | 561.26 |
分子式 | C25H23Br2NO4 |
CAS No. | 500794-88-7 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (89.13 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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TR antagonist 1 500794-88-7 Endocrinology/Hormones Thyroid hormone receptor(THR) Inhibitor inhibitor inhibit