store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TTA-Q6 is a selective T-type Ca2+ channel antagonist with potential antitumor and immunomodulatory activity for the treatment of neurological disorders by inhibiting the uptake of extracellular calcium ions by tumor cells and inducing intracellular calcium deficiency and endoplasmic reticulum (ER) stress.
説明 | TTA-Q6 is a selective T-type Ca2+ channel antagonist with potential antitumor and immunomodulatory activity for the treatment of neurological disorders by inhibiting the uptake of extracellular calcium ions by tumor cells and inducing intracellular calcium deficiency and endoplasmic reticulum (ER) stress. |
In vitro | In the acidic tumor microenvironment, TTA-Q6 is released, disrupting cancer cell calcium uptake, inducing endoplasmic reticulum stress, and promoting the translocation of calcium-binding proteins to the cell surface[1]. |
分子量 | 405.8 |
分子式 | C20H15ClF3N3O |
CAS No. | 910484-28-5 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (246.43 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TTA-Q6 910484-28-5 Membrane transporter/Ion channel Metabolism Calcium Channel TTA-Q-6 TTA Q6 TTAQ6 Inhibitor inhibitor inhibit