Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-PEG-C2-NH2 hydrochloride can be used in the synthesis of PROTACs.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 12,000 | |||
10 mg | 在庫あり | ¥ 17,000 | |||
25 mg | 在庫あり | ¥ 28,000 | |||
50 mg | 在庫あり | ¥ 41,000 | |||
100 mg | 在庫あり | ¥ 61,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 15,000 |
説明 | Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-PEG-C2-NH2 hydrochloride can be used in the synthesis of PROTACs. |
In vitro | PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
分子量 | 454.862 |
分子式 | C19H23ClN4O7 |
CAS No. | 2204226-02-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 100 mg/mL (219.85 mM), Sonication is recommended.
DMSO: 125 mg/mL (274.81 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Thalidomide-O-amido-PEG-C2-NH2 hydrochloride 2204226-02-6 Others PROTAC E3 Ligase Ligand-Linker Conjugate Inhibitor Thalidomide-O-amido-PEG-C2-NH2 Hydrochloride Thalidomide-O-amido-PEG-C-2-NH2 hydrochloride ThalidomideOamidoPEGC2NH2 hydrochloride inhibit Thalidomide O amido PEG C2 NH2 hydrochloride E3 Ligase Ligand-Linker Conjugates inhibitor