Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tin-protoporphyrin IX is a potent inhibitor of Heme oxygenase-1 (HO-1). It sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice models.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
5 mg | 約 35 days | ¥ 28,500 |
10 mg | 約 35 days | ¥ 53,000 |
25 mg | 約 35 days | ¥ 124,000 |
50 mg | 約 35 days | ¥ 218,000 |
説明 | Tin-protoporphyrin IX is a potent inhibitor of Heme oxygenase-1 (HO-1). It sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice models. |
ターゲット&IC50 | HO-1: |
In vitro | Tin-protoporphyrin IX with 20 μM, 50 μM and 24 hours, significantly suppressed the proliferation of Capan-1 and CD18/HPAF cells. In contrast. |
In vivo | Tin-protoporphyrin IX (5 mg/kg; at 0, 7, 15, and 20 days) intraperitoneal injection alone or combines with Gemcitabine significantly reduced the weight of pancreatic tumors (P < 0.05), decreases metastasis and improved the efficacy of Gemcitabine treatment. |
別名 | SnPPIX |
分子量 | 749.26 |
分子式 | C34H31Cl2N4O4Sn |
CAS No. | 14325-05-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Tin-protoporphyrin IX 14325-05-4 Others Tinprotoporphyrin IX Tin protoporphyrin IX SnPPIX Inhibitor inhibitor inhibit