keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tirzepatide (LY-3298176) is a dual agonist of glucose-dependent polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor with neuroprotective activity for the study of diabetes and obesity.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 61,000 |
5 mg | 在庫あり | ¥ 160,500 |
10 mg | 在庫あり | ¥ 228,000 |
25 mg | 在庫あり | ¥ 337,500 |
50 mg | 在庫あり | ¥ 457,000 |
100 mg | 在庫あり | ¥ 615,000 |
説明 | Tirzepatide (LY-3298176) is a dual agonist of glucose-dependent polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor with neuroprotective activity for the study of diabetes and obesity. |
In vitro | In SHSY5Y cells, treatment with Tirzepatide (0-0.4 μM; 7 days) upregulated the mRNA expression and protein levels of both CREB and BDNF, while increasing the protein levels of Bcl-2, pAkt, MAP2, GAP43, AGBL4, GLUT4, and SORBS1[1]. |
In vivo | In diet-induced obese (DIO) mice, treatment with Tirzepatide (10 nM/kg; subcutaneous injection) resulted in reduced body weight and food consumption, as well as decreased levels of glucose, insulin, leptin, and C-peptide[2]. |
別名 | LY-3298176 |
分子量 | 4813.45 |
分子式 | C225H348N48O68 |
CAS No. | 2023788-19-2 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (20.78 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Tirzepatide 2023788-19-2 GPCR/G Protein Glucagon Receptor LY3298176 LY-3298176 LY 3298176 Inhibitor inhibitor inhibit