keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF).
説明 | Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF). |
ターゲット&IC50 | CRF2β (mouse): 0.5 nM, CRF1 (human):0.4nM, CRF2α (rat):0.3 nM |
In vitro | Urocortin, human is a selective agonist of CRF2?receptor, with Kis of 0.4, 0.3, and 0.5 nM for human CRF1, rat CRF2α?and mouse CRF2β?receptors in cell assay, respectively[1]. |
In vivo | Urocortin (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats and such a effect also observed in mice after 1 μg of Urocortin i.c.v. administration. It appears to be a more potent suppressor of ingestive behavior. Urocortin has the potential of inducing anxiogenic behavior[2]. |
別名 | Urocortin (human), Human urocortin, Human urocortin 1, Human urocortin I |
分子量 | 4696.32 |
分子式 | C204H337N63O64 |
CAS No. | 176591-49-4 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Urocortin, human 176591-49-4 GPCR/G Protein CRFR Corticotropin-releasing Factor Receptor Urocortin (human) Human urocortin Human urocortin 1 Human urocortin1 inhibit Human urocortin-1 Human urocortin I Urocortin Inhibitor inhibitor