Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Veledimex S enantiomer is the S enantiomer of veledimex. Veledimex is an oral activator ligand for a proprietary gene therapy promoter system and CYP3A4/5 inhibitor.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | Veledimex S enantiomer is the S enantiomer of veledimex. Veledimex is an oral activator ligand for a proprietary gene therapy promoter system and CYP3A4/5 inhibitor. |
In vivo | Ad-RTS-mIL-12 + veledimex have demonstrated a dose-related increase in tumor IL-12 mRNA and IL-12 protein expression.In numerous syngeneic mouse tumor models, Discontinuation of veledimex resulted in a return to baseline IL-12 mRNA and protein expression. Veledimex crosses the blood-brain-barrier in both naive and orthotopic GL-261 mice with increased brain tissue level of -6 fold observed in tumor bearing vs. normal mice. Ad-RTS-mIL-12 + veledimex demonstrate a dose-related increase in survival without significant adverse events[2]. |
別名 | RG-115932 S enantiome, INXN-1001 S enantiome |
分子量 | 438.6 |
分子式 | C27H38N2O3 |
CAS No. | 1093131-03-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Veledimex (S enantiomer) 1093131-03-3 Others RG-115932 S enantiome INXN-1001 S enantiome Veledimex Inhibitor inhibitor inhibit