Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ac-YVAD-CHO (L-709049) acetate is a potent, reversible, and specific tetrapeptide interleukin-1β converting enzyme (ICE) inhibitor, demonstrating specificity for caspase-1 as well. It exhibits K_i values of 3.0 nM in mice and 0.76 nM in humans, underscoring its efficacy. Additionally, Ac-YVAD-CHO acetate has the capacity to inhibit the production of mature IL-1β, highlighting its therapeutic potential [1] [2] [3].
説明 | Ac-YVAD-CHO (L-709049) acetate is a potent, reversible, and specific tetrapeptide interleukin-1β converting enzyme (ICE) inhibitor, demonstrating specificity for caspase-1 as well. It exhibits K_i values of 3.0 nM in mice and 0.76 nM in humans, underscoring its efficacy. Additionally, Ac-YVAD-CHO acetate has the capacity to inhibit the production of mature IL-1β, highlighting its therapeutic potential [1] [2] [3]. |
分子量 | 552.57 |
分子式 | C25H36N4O10 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Ac-YVAD-CHO acetate Inhibitor inhibitor inhibit