store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ACTH (1-17) acetate is a potent agonist at the human melanocortin 1 (MC1) receptor with high affinity(Ki = 0.21 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 28,000 | |||
5 mg | 在庫あり | ¥ 94,500 | |||
10 mg | 在庫あり | ¥ 135,000 | |||
25 mg | 在庫あり | ¥ 242,500 | |||
50 mg | 在庫あり | ¥ 364,000 | |||
100 mg | 在庫あり | ¥ 545,500 |
説明 | ACTH (1-17) acetate is a potent agonist at the human melanocortin 1 (MC1) receptor with high affinity(Ki = 0.21 nM). |
ターゲット&IC50 | MC1R (human):0.21 nM(Ki) |
In vitro | ACTH (1-17) acetate induces a slight and not significant increase in growth hormone secretion even when micromolar concentrations of the peptide are employed in rat pituitary cultures[1]. ACTH (1-17) acetate showed an affinity for alpha-MSH with Ki of 0.13±0.005 nM[1]. |
In vivo | When nocturnal animals became active, inhibition of DNA markers was noted when ACTH (1-17) acetate was administered 2 hours after the start of the daily dark span. When administered during this circadian phase, particularly larger doses were associated with a 24-hour lasting inhibition of DNA markers. When the same dose was injected 4 hours earlier, the inhibitory effect was much shorter [2]. |
分子量 | 2153.47 |
分子式 | C97H149N29O25S |
store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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ACTH (1-17) acetate GPCR/G Protein Neuroscience Melanocortin Receptor ACTH ACTH (117) acetate ACTH (1 17) acetate ACTH Acetate Inhibitor inhibitor inhibit