Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Anti-osteoporosis agent-4 (Compound 11h) suppresses the differentiation of primary osteoclasts and attenuates RANKL-induced osteoclastogenesis. It effectively inhibits osteoclast formation, demonstrating an IC50 value of 358.29 nM, and impedes the activation of the PI3K/AKT and IκBα/NF-κB signaling pathways [1].
説明 | Anti-osteoporosis agent-4 (Compound 11h) suppresses the differentiation of primary osteoclasts and attenuates RANKL-induced osteoclastogenesis. It effectively inhibits osteoclast formation, demonstrating an IC50 value of 358.29 nM, and impedes the activation of the PI3K/AKT and IκBα/NF-κB signaling pathways [1]. |
分子量 | 560.02 |
分子式 | C26H26ClN3O7S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Anti-osteoporosis agent-4 NF-Κb NF-κB Inhibitor inhibitor inhibit