Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones. Antibacterial agent 105 exhibits antibacterial activity against M. tuberculosis with MIC 90 of 2.64 μM. Moreover, Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC 90 s of 11.18, 11.18,0.70,1.40,44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum, BCG, E. aerogenes and S. aureus, respectively [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones. Antibacterial agent 105 exhibits antibacterial activity against M. tuberculosis with MIC 90 of 2.64 μM. Moreover, Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC 90 s of 11.18, 11.18,0.70,1.40,44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum, BCG, E. aerogenes and S. aureus, respectively [1]. |
In vitro | Antibacterial agent 105 (compound 17) demonstrates an inhibitory effect on the growth of M. tuberculosis within in vitro cultured macrophages and exhibits antibacterial activities against fluoroquinolone-resistant bacteria and extensively drug-resistant tuberculosis (XDR-TB), as shown in [1]. Notably, it exhibits no toxicity towards the Vero cell line and human macrophages after 24 hours of exposure [1]. |
分子量 | 299.24 |
分子式 | C14H9N3O5 |
CAS No. | 2364493-24-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Antibacterial agent 105 2364493-24-1 Inhibitor inhibitor inhibit