Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antiproliferative Agent-17 exhibits both antimicrobial properties against Gram-positive bacteria and anticancer activity [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | Antiproliferative Agent-17 exhibits both antimicrobial properties against Gram-positive bacteria and anticancer activity [1]. |
In vitro | Antiproliferative agent-17 (compound 5e) exhibited activity against Gram-positive bacteria, including Staphylococcus aureus IFO 3060, Bacillus subtilis IFO 3007, and Micrococcus luteus IFO 3232. It showed no activity against the tested Gram-negative bacteria and fungi [1]. Compound 5e demonstrated antiproliferative effects with IC50 values of 12.85 μM for PC-3 (human prostate cancer), 11.96 μM for HCT-116 (human colorectal cancer), 16.30 μM for HepG-2 (human hepatocellular carcinoma), 9.87 μM for HeLa (human cervical cancer), and 6.90 μM for MCF-7 (human breast cancer) [1]. Additionally, it binds to the active site of the SIRT1 enzyme, occupying the positions of the NAD cofactor and the known histone deacetylase inhibitor EX527 [1]. |
分子量 | 416.58 |
分子式 | C26H28N2OS |
CAS No. | 2882206-08-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Antiproliferative agent-17 2882206-08-6 Inhibitor inhibitor inhibit