Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antitumor agent-38 is a highly effective antitumor compound that exhibits antiproliferative activity towards cancer cells. It induces cell cycle arrest specifically at the late S and G2/M phase, while not impeding microtubule formation or altering cell morphology [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約8-10 週間 | ¥ 491,500 |
50 mg | 約8-10 週間 | ¥ 639,500 |
100 mg | 約8-10 週間 | ¥ 808,000 |
説明 | Antitumor agent-38 is a highly effective antitumor compound that exhibits antiproliferative activity towards cancer cells. It induces cell cycle arrest specifically at the late S and G2/M phase, while not impeding microtubule formation or altering cell morphology [1]. |
In vitro | Antitumor agent-38 (compound 9h) demonstrates antiproliferative effects, exhibiting GI50 values of 0.66, 0.85, 0.76, 4.12, and 3.67 μM against A549, MDA-MB-231, KB, KB-VIN, and MCF-7 cells, respectively [1]. Furthermore, this compound (0.58, 1.74 μM; 24 h) significantly induces cell cycle arrest at the late S and G2/M phases in MDA-MB-231 cells, as evidenced by Cell Cycle Analysis, which was conducted at concentrations of 0.85 and 1.74 μM over 24 hours, confirming the arrest occurred at the specified phases [1]. |
分子量 | 380.44 |
分子式 | C22H24N2O4 |
CAS No. | 2744193-34-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Antitumor agent-38 2744193-34-6 Inhibitor inhibitor inhibit