Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AS-99 is a first-in-class, potent, and selective inhibitor of the ASH1L histone methyltransferase, exhibiting anti-leukemic activity with an IC50 value of 0.79 µM and a Kd of 0.89 µM. It inhibits cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and effectively reduces leukemia burden in vivo.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約8-10 週間 | ¥ 486,500 |
50 mg | 約8-10 週間 | ¥ 638,000 |
100 mg | 約8-10 週間 | ¥ 849,500 |
説明 | AS-99 is a first-in-class, potent, and selective inhibitor of the ASH1L histone methyltransferase, exhibiting anti-leukemic activity with an IC50 value of 0.79 µM and a Kd of 0.89 µM. It inhibits cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and effectively reduces leukemia burden in vivo. |
分子量 | 630.14 |
分子式 | C27H31ClF3N5O3S2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AS-99 Inhibitor inhibitor inhibit