Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aviculin, a lignan glycoside, exhibits significant anticancer properties, particularly in inhibiting the metabolic activity of MCF-7 cells to below 50%, with an IC 50 value of 75.47 μM. It promotes apoptosis in breast cancer cells via the intrinsic apoptosis pathway, enhancing the expression of initiator caspase-9, executioner caspase-7, and poly (ADP-ribose) polymerase (PARP). Furthermore, Aviculin leads to an increased Bax/Bcl-2 ratio, underlying its potential as an effective anticancer agent.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | お問い合わせ | ¥ 349,000 |
50 mg | お問い合わせ | ¥ 454,500 |
100 mg | お問い合わせ | ¥ 574,000 |
説明 | Aviculin, a lignan glycoside, exhibits significant anticancer properties, particularly in inhibiting the metabolic activity of MCF-7 cells to below 50%, with an IC 50 value of 75.47 μM. It promotes apoptosis in breast cancer cells via the intrinsic apoptosis pathway, enhancing the expression of initiator caspase-9, executioner caspase-7, and poly (ADP-ribose) polymerase (PARP). Furthermore, Aviculin leads to an increased Bax/Bcl-2 ratio, underlying its potential as an effective anticancer agent. |
分子量 | 506.54 |
分子式 | C26H34O10 |
CAS No. | 156765-33-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Aviculin 156765-33-2 Inhibitor inhibitor inhibit