Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Banoxantrone (AQ4N), a hypoxia-selective cytotoxin prototype, undergoes reduction to AQ4, effectively inhibiting topoisomerase II. It selectively targets and eradicates hypoxic cells through an iNOS-dependent mechanism. This compound demonstrates significant cytotoxicity with its hypoxia-selective action being augmented by radiation.
説明 | Banoxantrone (AQ4N), a hypoxia-selective cytotoxin prototype, undergoes reduction to AQ4, effectively inhibiting topoisomerase II. It selectively targets and eradicates hypoxic cells through an iNOS-dependent mechanism. This compound demonstrates significant cytotoxicity with its hypoxia-selective action being augmented by radiation. |
別名 | AQ4N |
分子量 | 444.48 |
分子式 | C22H28N4O6 |
CAS No. | 136470-65-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Banoxantrone 136470-65-0 AMPK Activator SC4 SC4 SC4 AMPK Activator AQ4N SC 4 Inhibitor inhibitor inhibit