Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BLX3887 is an inhibitor of 15-lipoxygenase type 1 (15-LO-1; IC50 = 32 nM in a cell-free enzyme assay).1 It is selective for 15-LO-1 over 15-LO-2, which it does not inhibit, 5-LO (IC50 = 472 nM), and 12-LO (IC50 = 3,310 nM). BLX3887 inhibits the production of 15-LO metabolites selectively in eosinophils over neutrophils when used at a concentration of 10 μM. It also inhibits endocytosis in, and the migration of, isolated human peripheral blood mononuclear cell-derived dendritic cells in vitro.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
500 μg | 約 35 days | ¥ 18,000 |
1 mg | 約 35 days | ¥ 35,500 |
5 mg | 約 35 days | ¥ 136,500 |
10 mg | 約 35 days | ¥ 243,500 |
説明 | BLX3887 is an inhibitor of 15-lipoxygenase type 1 (15-LO-1; IC50 = 32 nM in a cell-free enzyme assay).1 It is selective for 15-LO-1 over 15-LO-2, which it does not inhibit, 5-LO (IC50 = 472 nM), and 12-LO (IC50 = 3,310 nM). BLX3887 inhibits the production of 15-LO metabolites selectively in eosinophils over neutrophils when used at a concentration of 10 μM. It also inhibits endocytosis in, and the migration of, isolated human peripheral blood mononuclear cell-derived dendritic cells in vitro. |
分子量 | 308.52 |
分子式 | C10H5Cl3FN3O |
CAS No. | 934758-70-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 30 mg/mL
DMSO: 15 mg/mL
DMSO:PBS (pH 7.2) (1:5): 0.16 mg/mL
You can also refer to dose conversion for different animals. 詳細
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BLX3887 934758-70-0 BLX-3887 BLX 3887 Inhibitor inhibitor inhibit