Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMS-986318 is a potent nonbile acid FXR agonist, displaying EC50 values of 53 nM and 350 nM in FXR Gal4 and SRC-1 recruitment assays, respectively. It exhibits a favorable ADME profile and shows effectiveness in mouse models of liver cholestasis and fibrosis caused by bile duct ligation. BMS-986318 is employed in research focusing on nonalcoholic steatohepatitis.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約8-10 週間 | ¥ 486,500 |
50 mg | 約8-10 週間 | ¥ 638,000 |
100 mg | 約8-10 週間 | ¥ 849,500 |
説明 | BMS-986318 is a potent nonbile acid FXR agonist, displaying EC50 values of 53 nM and 350 nM in FXR Gal4 and SRC-1 recruitment assays, respectively. It exhibits a favorable ADME profile and shows effectiveness in mouse models of liver cholestasis and fibrosis caused by bile duct ligation. BMS-986318 is employed in research focusing on nonalcoholic steatohepatitis. |
分子量 | 615.43 |
分子式 | C30H23Cl2F3N4O3 |
CAS No. | 2314378-09-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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BMS-986318 2314378-09-9 Inhibitor inhibitor inhibit