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Brodalumab (AMG 827) is a human monoclonal antibody targeting interleukin 17 receptor (IL-17R) IgG2, often used as an immunosuppressant in the treatment of psoriasis and psoriasis.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 35,500 |
5 mg | 在庫あり | ¥ 91,500 |
10 mg | 在庫あり | ¥ 133,500 |
25 mg | 在庫あり | ¥ 214,500 |
50 mg | 在庫あり | ¥ 291,500 |
説明 | Brodalumab (AMG 827) is a human monoclonal antibody targeting interleukin 17 receptor (IL-17R) IgG2, often used as an immunosuppressant in the treatment of psoriasis and psoriasis. |
In vitro |
Brodalumab (AMG 827) blocks the biological activity of the IL-17A, IL-17F, and IL-17A/F heterodimer signaling pathways by binding to the IL-17RA/RC complex. Additionally, it inhibits the biological activity of the IL-25 (IL-17E) signaling pathway by binding to the IL-17RA/RB complex[1]. Brodalumab is capable of suppressing the inflammatory processes associated with psoriasis[1]. |
別名 | LP 0160, KHK-4827, AMG-827 |
分子量 | N/A |
CAS No. | 1174395-19-7 |
store at low temperature
store at -20°C
You can also refer to dose conversion for different animals. 詳細
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Brodalumab 1174395-19-7 Immunology/Inflammation IL Receptor LP 0160 KHK-4827 AMG-827 Inhibitor inhibitor inhibit