store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
cAC 253 acetate (TP2135 Free base) is an amylin antagonist. cAC 253 acetate inhibits 125I-adrenomedullin binding, with an IC50 of 25 nM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 45,000 | |||
5 mg | 在庫あり | ¥ 102,500 | |||
10 mg | 在庫あり | ¥ 151,500 | |||
25 mg | 在庫あり | ¥ 226,500 | |||
50 mg | 在庫あり | ¥ 317,000 |
説明 | cAC 253 acetate (TP2135 Free base) is an amylin antagonist. cAC 253 acetate inhibits 125I-adrenomedullin binding, with an IC50 of 25 nM. |
In vitro | cAC 253 acetate (5-20 μM) antagonizes adrenomedullin-stimulated cAMP production at micromolar concentrations[1]. cAC 253 acetate (5-10 μM) blocks increases in intracellular Ca2+, activation of protein kinase A, MAPK, Akt, cFos, and cell death, which occur upon AMY3 activation with hAmylin, Aβ1-42, or their co-application[2]. cAC 253 acetate (10 nM) blocks Aβ1-42-induced electrophysiological effects[3]. |
別名 | cAC 253 acetate (TP2135 Free base) |
分子量 | 3069.39 |
分子式 | C128H206N42O42S2 |
CAS No. | TP2135L |
store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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cAC 253 acetate TP2135L GPCR/G Protein Amylin Receptor cAC 253 acetate (TP2135 Free base) TP 2135 TP2135 Free base cAC 253 Acetate cAC-253 Acetate cAC253 Acetate TP2135 TP-2135 Inhibitor inhibitor inhibit