Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Carbonic Anhydrase Inhibitor 12 is a potent inhibitor of CA II, with additional inhibitory activity against CA I, exhibiting K_i values of 1.72 nM for CA II and 271 nM for CA I. Moreover, it demonstrates significant anticancer activity across various cancer cell lines [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約8-10 週間 | ¥ 349,000 |
50 mg | 約8-10 週間 | ¥ 454,500 |
100 mg | 約8-10 週間 | ¥ 574,000 |
説明 | Carbonic Anhydrase Inhibitor 12 is a potent inhibitor of CA II, with additional inhibitory activity against CA I, exhibiting K_i values of 1.72 nM for CA II and 271 nM for CA I. Moreover, it demonstrates significant anticancer activity across various cancer cell lines [1]. |
In vitro | Compound 14h, a carbonic anhydrase inhibitor 12 at a concentration of 10 µM for 48 hours (single dose), significantly affects the specificity and the inhibitory potency across various cancer cell lines [1]. At concentrations of 2.4 µM in MCF-7 and 2.5 µM in MDA-MB-231 for the same duration, the compound induces cell cycle arrest at the G2/M phase and increases both early and late apoptotic phases relative to control untreated cells [1]. |
分子量 | 640.53 |
分子式 | C27H22BrN5O5S2 |
CAS No. | 2883451-38-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Carbonic anhydrase inhibitor 12 2883451-38-3 Metabolism Carbonic Anhydrase Inhibitor inhibitor inhibit