Powder: -20°C for 3 years | In solvent: -80°C for 1 year
The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 μM compared to 20 μM by resveratrol.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 mg | 約 35 days | ¥ 26,000 |
50 mg | 約 35 days | ¥ 114,000 |
100 mg | 約 35 days | ¥ 201,500 |
500 mg | 約 35 days | ¥ 877,000 |
説明 | The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 μM compared to 20 μM by resveratrol. |
分子量 | 228.266 |
分子式 | C15H13FO |
CAS No. | 139141-12-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF:PBS (pH 7.2) (1:2): 0.3 mg/mL
DMSO: 2 mg/mL
Ethanol: 0.5 mg/mL
DMF: 3 mg/mL
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CAY10512 139141-12-1 CAY 10512 CAY-10512 Inhibitor inhibitor inhibit