Powder: -20°C for 3 years | In solvent: -80°C for 1 year
The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPARα, γ, and δ with IC50 values of 113, 50, and 223 nM, respectively. It potently transactivates PPARα, γ, and δ with EC50 values of 8, 70, and 500 nM, respectively. CAY10573 demonstrates stronger binding and functional activity for PPARγ than the antidiabetic compound rosiglitazone (IC50 = 92 nM; EC50 = 220 nM).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 約 35 days | ¥ 48,500 |
5 mg | 約 35 days | ¥ 196,000 |
10 mg | 約 35 days | ¥ 340,000 |
説明 | The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPARα, γ, and δ with IC50 values of 113, 50, and 223 nM, respectively. It potently transactivates PPARα, γ, and δ with EC50 values of 8, 70, and 500 nM, respectively. CAY10573 demonstrates stronger binding and functional activity for PPARγ than the antidiabetic compound rosiglitazone (IC50 = 92 nM; EC50 = 220 nM). |
分子量 | 521.6 |
分子式 | C33H31NO5 |
CAS No. | 853652-40-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 0.3 mg/mL
DMSO: 0.5 mg/mL
You can also refer to dose conversion for different animals. 詳細
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CAY10573 853652-40-1 Others CAY 10573 CAY-10573 Inhibitor inhibitor inhibit