Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CAY10726 is an arylurea fatty acid. It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 μM. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 約 35 days | ¥ 18,000 |
5 mg | 約 35 days | ¥ 80,000 |
10 mg | 約 35 days | ¥ 136,500 |
25 mg | 約 35 days | ¥ 305,500 |
説明 | CAY10726 is an arylurea fatty acid. It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 μM. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane. |
In vivo | In vivo, CAY10726 (2.5-40 mg/kg) reduces tumor volume and increases tumor cell apoptosis in a mouse MDA-MB-231 breast cancer xenograft model in a dose-dependent manner. |
別名 | CAY10726 |
分子量 | 493 |
分子式 | C24H36ClF3N2O3 |
CAS No. | 1611446-66-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mg/mL
Ethanol: 12 mg/mL
DMF:PBS(pH7.2) (1:2): 0.33 mg/mL
DMF: 20 mg/mL
You can also refer to dose conversion for different animals. 詳細
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CAY10726 1611446-66-2 Others CAY 10726 CAY-10726 Inhibitor inhibitor inhibit