Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDK9 Antagonist-1 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form PROTAC[1].
説明 | CDK9 Antagonist-1 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form PROTAC[1]. |
In vitro | CDK9: 17 μM (IC50, MCF-7 cells) |
別名 | CDK9 Antagonist-1 |
分子量 | N/A |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
You can also refer to dose conversion for different animals. 詳細
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CDK9 Antagonist-1 CDK9 Antagonist1 CDK-9 Antagonist-1 CDK9 Antagonist 1 Inhibitor inhibitor inhibit