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Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cancer and squamous cell skin cancer research.
説明 | Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cancer and squamous cell skin cancer research. |
In vivo | In a mouse model with MC38.Ova tumors, Cemiplimab (i.p., 10 mg/kg, five injections within 2 weeks) increased the proportion of effector T cells in tumors and dLNs, resulting in reduced tumor growth when combined with immunotherapy using REGN3767[2]. |
別名 | REGN-2810, SAR-439684 |
分子量 | N/A |
CAS No. | 1801342-60-8 |
store at low temperature
store at -20°C
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Cemiplimab 1801342-60-8 Others REGN 2810 REGN-2810 REGN2810 SAR 439684 SAR439684 SAR-439684 Inhibitor inhibitor inhibit