Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Compound 48/80, also known as Poly-p-methoxyphenethylmethylamine, is a commonly utilized mast cell activator in animal and tissue models. This compound exerts its effect by stimulating trimeric G-proteins at the mast cell membrane, triggering degranulation through both phospholipase C and D pathways.
説明 | Compound 48/80, also known as Poly-p-methoxyphenethylmethylamine, is a commonly utilized mast cell activator in animal and tissue models. This compound exerts its effect by stimulating trimeric G-proteins at the mast cell membrane, triggering degranulation through both phospholipase C and D pathways. |
In vitro | Compound 48/80 (poly-p-methoxyphenethylmethylamine), widely employed to induce mast cell degranulation, effectively inhibits the growth of L1210 and Friend leukemic cells at concentrations ranging from 5-20 μg/ml in vitro. This action results in the production of polykaryons, characterized as large multinucleated cells[3]. |
別名 | Poly-p-methoxyphenethylmethylamine |
分子量 | 519.73 |
分子式 | C32H45N3O3 |
CAS No. | 94724-12-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Compound 48/80 94724-12-6 Poly-p-methoxyphenethylmethylamine Inhibitor inhibitor inhibit