store at low temperature
store at -80°C
Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking the interaction of this domain with the FXa active site. Injections of Concizumab increase thrombin in the blood and can be used to prevent and treat hemophilia.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 66,500 |
5 mg | 在庫あり | ¥ 173,500 |
10 mg | 在庫あり | ¥ 273,500 |
25 mg | 在庫あり | ¥ 408,500 |
50 mg | 在庫あり | ¥ 558,000 |
100 mg | 在庫あり | ¥ 750,500 |
説明 | Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking the interaction of this domain with the FXa active site. Injections of Concizumab increase thrombin in the blood and can be used to prevent and treat hemophilia. |
In vitro | In a concentration-dependent manner, Concizumab increases the peak value of thrombin [1]. |
In vivo | In cynomolgus monkeys, Concizumab (i.v./s.c.) blocked the interaction between TFPI and FXa active site [2]. |
別名 | mAb 2021, NN 7415 |
分子量 | N/A |
CAS No. | 1312299-39-0 |
store at low temperature
store at -80°C
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Concizumab 1312299-39-0 Others mAb 2021 NN 7415 NN-7415 NN7415 Inhibitor inhibitor inhibit