Powder: -20°C for 3 years | In solvent: -80°C for 1 year
D-myo-Inositol-1,4,6-phosphate (Ins(1,4,6)-P3) is a member of the inositol phosphate (InsP) family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)-P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,4,6)-P3 (tested as the meso compound) is 9-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.
説明 | D-myo-Inositol-1,4,6-phosphate (Ins(1,4,6)-P3) is a member of the inositol phosphate (InsP) family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)-P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,4,6)-P3 (tested as the meso compound) is 9-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes. |
分子量 | 443.082 |
分子式 | C6H15NaO15P3 |
CAS No. | 157380-18-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 50 mg/mL
You can also refer to dose conversion for different animals. 詳細
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D-myo-Inositol-1,4,6-triphosphate (sodium salt) 157380-18-2 Others D myo Inositol 1,4,6 triphosphate (sodium salt) D-myo-Inositol-1,4,6-triphosphate DmyoInositol1,4,6triphosphate (sodium salt) Inhibitor inhibitor inhibit