Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N(G)-Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N(G)-nitro-L-arginine methyl ester . D-NAME was initially thought to be inactive and was often used as a negative control for L-NAME. Later studies showed that D-NAME (40 mg/kg/day in rats) can have similar but less pronounced effects as L-NAME (40 mg/kg/day in rats) in the cardiovascular system, particularly at long-term timepoints. D-NAME (3-10 µg/mouse) had no effect on nociception in mice assessed using the tail flick test.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
250 mg | 約 35 days | ¥ 18,000 |
500 mg | 約 35 days | ¥ 34,000 |
1 g | 約 35 days | ¥ 61,500 |
5 g | 約 35 days | ¥ 268,500 |
説明 | N(G)-Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N(G)-nitro-L-arginine methyl ester . D-NAME was initially thought to be inactive and was often used as a negative control for L-NAME. Later studies showed that D-NAME (40 mg/kg/day in rats) can have similar but less pronounced effects as L-NAME (40 mg/kg/day in rats) in the cardiovascular system, particularly at long-term timepoints. D-NAME (3-10 µg/mouse) had no effect on nociception in mice assessed using the tail flick test. |
分子量 | 269.69 |
分子式 | C7H16ClN5O4 |
CAS No. | 50912-92-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBS (pH 7.2): 10 mg/mL
DMF: 20 mg/mL
DMSO: 20 mg/mL
You can also refer to dose conversion for different animals. 詳細
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D-NAME (hydrochloride) 50912-92-0 D NAME (hydrochloride) DNAME (hydrochloride) D-NAME Inhibitor inhibitor inhibit