Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dopamine D4 receptor antagonist-1 can be used in schizophrenia study. Dopamine D4 receptor antagonist-1 is a selective antagonist of Dopamine D4 receptor (DRD4). The Ki value of Dopamine D4 receptor antagonist-1 for Hd4.2 is 9.0 nM [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | Dopamine D4 receptor antagonist-1 can be used in schizophrenia study. Dopamine D4 receptor antagonist-1 is a selective antagonist of Dopamine D4 receptor (DRD4). The Ki value of Dopamine D4 receptor antagonist-1 for Hd4.2 is 9.0 nM [1]. |
In vivo | Dopamine D4 receptor antagonist-1, administered intraperitoneally at a dosage of 10 mg/kg in a single dose, exhibits an inhibitory effect on catecholaminergic systems, specifically leading to increased dopamine (DOPA) accumulation in the hippocampus, with no significant effect on the striatum [1]. This observation was made in male Long-Evans rats weighing 180-250 g, dopamine D4 receptor locus knockout mice (D4 KO), and wild-type rats (WT). |
分子量 | 326.82 |
分子式 | C18H19ClN4 |
CAS No. | 444724-92-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Dopamine D4 receptor antagonist-1 444724-92-9 Inhibitor inhibitor inhibit