Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dyrk1A-IN-5 (compound 5j) is a highly potent and selective inhibitor of DYRK1A, exhibiting an IC50 of 6 nM. It dose-dependently diminishes the phosphorylation of Thr434 in SF3B1, with an IC50 of 0.5 μM. Moreover, Dyrk1A-IN-5 effectively inhibits the phosphorylation of tau at Thr212, with an IC50 of 2.1 μM. Given these properties, Dyrk1A-IN-5 is a valuable tool for Down syndrome research [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 245,500 |
50 mg | 約6-8 週間 | ¥ 319,000 |
100 mg | 約6-8 週間 | ¥ 503,000 |
説明 | Dyrk1A-IN-5 (compound 5j) is a highly potent and selective inhibitor of DYRK1A, exhibiting an IC50 of 6 nM. It dose-dependently diminishes the phosphorylation of Thr434 in SF3B1, with an IC50 of 0.5 μM. Moreover, Dyrk1A-IN-5 effectively inhibits the phosphorylation of tau at Thr212, with an IC50 of 2.1 μM. Given these properties, Dyrk1A-IN-5 is a valuable tool for Down syndrome research [1]. |
分子量 | 388.16 |
分子式 | C16H9IN2O2 |
CAS No. | 1685235-41-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Dyrk1A-IN-5 1685235-41-9 Inhibitor inhibitor inhibit